- Acarbose is available in 50mg or 100mg tablets.
Treatment of type 2 diabetes in adults where physical activity and dietary management has not resulted in adequate glycaemic targets.
For the most up to date PBS therapeutic indications for sitagliptin, please see:
- The average adult dose of acarbose is 100mg three times a day just before each meal. However occasionally there is a need to increase this to 200mg three times a day.
- To prevent gastrointestinal side effects (boating, flatulence, nausea)
- Start at 50mg once a day for one week.
- Increase to 50mg twice a day for the second week.
- Then increase to 50mg three times a day after the third week.
- Further increases in the dose may occur depending on glucose levels 6-8 weeks later.
A diet lower in complex carbohydrates and cane sugar (sucrose) may also help reduce the side effect prolife.
- No modification in the dose is necessary in the elderly.
- Acarbose may affect digoxin availability.
- Gastrointestinal side effects including diarrhoea, flatulence, nausea, and loose stools.
- A dose reduction or a change in the diet often helps reduce these side effects.
- Hypersensitivity to acarbose or any active ingredient
- Individuals under the age of 18 years
- Severe renal impairment: Acarbose is contraindicated in individuals with severe renal impairment (creatinine clearance < 25 mL/min).
Note: Diabetes MedsCheck with referral for annual cycle of care for screening.
- Any form of malabsorption syndrome including Crohn’s disease, ulcerative colitis, intestinal obstruction or ileus, and intestinal ulcers.
- Only an exceedingly small amount of acarbose is absorbed (1-2%) by the gastrointestinal tract.
- The small amount of acarbose that is absorbed is excreted unchanged by the kidneys.
For more detailed information on this product please consult the product information.